About Kidney Stones

Kidneys are designed to remove waste and fluid from the blood to make urine. If there is an excess of certain wastes (such as mineral and salt deposits) and not enough fluid in the blood, these wastes can build up and stick together in the kidneys, causing kidney stones.

The most common type of kidney stones are calcium stones, which are caused by a substance called calcium oxalate. For some people, these types of stones are caused by a condition called hyperoxaluria.

Hyperoxaluria is a condition in which there are high levels of oxalate in the urine. People with hyperoxaluria are at an increased risk for kidney stones and/or kidney damage.

Am I Eligible?

Hyperoxaluria that occurs in people with an underlying malabsorptive gastrointestinal (GI) condition that leads to absorption of too much oxalate from foods is called enteric hyperoxaluria.

Examples of these GI conditions include: Crohn’s disease, ulcerative colitis, or disorders of the pancreas due to cystic fibrosis or pancreatitis. You can also develop enteric hyperoxaluria after certain gastric bypass surgeries or surgery to remove a section of the intestine.

The uriROX‑2 Study